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Paper · arXiv

SpikeProphecy: A Large-Scale Benchmark for Autoregressive Neural Population Forecasting

Neural population models, which predict the joint firing of many simultaneously recorded neurons forward in time, are typically evaluated by a single aggregate Pearson correlation $r$ between predicted and actual spike counts, a number that masks critical structure. We argue that how we evaluate spike forecasting matters as much as what we build, and introduce SpikeProphecy, the first large-scale benchmark for causal, autoregressive spike-count forecasting on real electrophysiology recordings. Our core contribution is a population metric decomposition that separates aggregate performance into temporal fidelity, spatial pattern accuracy, and magnitude-invariant alignment. The decomposition...

AuthorsJohn R. Minnick, Jinghui Geng, Kamran Hussain et al.
Primary categoryq-bio.NC
Published13 May 2026
Last updated at source13 May 2026
q-bio.NCcs.LG
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