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Paper · arXiv

GenMed: A Pairwise Generative Reformulation of Medical Diagnostic Tasks

Data-driven medical AI is traditionally formulated as a discriminative mapping from input $X$ to output $Y$ via a learned function $f$, which does not generalize well across heterogeneous data and modalities encountered in real-world clinical settings. In this work, we propose a fundamentally different, generative paradigm. We model the joint distribution $P(X,Y)$ using diffusion models and reframe inference as a test-time output optimization problem. By guiding the generative process to match observed inputs, our framework enables flexible, gradient-based conditioning at inference time without architectural changes or retraining, effectively supporting arbitrary and previously unseen com...

AuthorsHantao Zhang, Weidong Guo, Yuhe Liu et al.
Primary categorycs.CV
Published11 May 2026
Last updated at source11 May 2026
cs.CV
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