Joint sparse coding and temporal dynamics support context reconfiguration
Adaptive behavior requires the brain to transition between distinct contexts while maintaining representations of prior experience. The ability to reconfigure neural representations without erasing previously acquired knowledge is central to learning in dynamic environments, yet the neural mechanisms that support this balance remain unclear. Understanding these mechanisms is also critical for addressing catastrophic forgetting in artificial systems designed for lifelong learning. Here, we identify joint sparse coding and temporal dynamics in both the mouse medial prefrontal cortex (mPFC) and computational networks as mechanisms that help preserve prior representations during context trans...
| Authors | Qianqian Shi, Yue Che, Faqiang Liu et al. |
|---|---|
| Primary category | q-bio.NC |
| Published | 11 May 2026 |
| Last updated at source | 11 May 2026 |
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