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Paper · arXiv

Active Multiple-Prediction-Powered Inference

Post-deployment monitoring of healthcare AI requires statistically valid, label-efficient methods, but gold-standard labels from clinician chart review are expensive. Prediction-powered inference (PPI) and active statistical inference (ASI) reduce label cost by combining a small labeled sample with abundant model predictions, but both are restricted to a single predictor, a poor fit for modern clinical pipelines that have multiple predictors of differing cost and accuracy available at inference time. We propose Active Multiple-Prediction-Powered Inference (AM-PPI), which routes each instance to a cost-appropriate predictor subset, samples gold-standard labels in proportion to the chosen s...

AuthorsNicholas Brawand, Nima Leclerc, Anhthy Ngo et al.
Primary categorystat.ML
Published8 May 2026
Last updated at source8 May 2026
stat.MLcs.LGstat.ME
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