External Validation of Deep Learning Models for BI-RADS Breast Density Prediction from Ultrasound Images
We externally validated three deep learning models (DenseNet121, ViT-B/32, and ResNet50) for predicting mammographic breast density from breast ultrasound exams on an independent cohort. The external validation set comprised 2,000 ultrasound exams, including 500 cancer cases defined by an initial negative exam (BI-RADS 1 or 2) followed by a cancer diagnosis within 6 months to 10 years, and 1,500 negative controls matched by manufacturer and study year. Performance was measured using patient-level AUROC across four density categories: A (fatty), B (scattered), C (heterogeneous), and D (extremely dense). As a downstream assessment, we also evaluated 10-year risk prediction by incorporating ...
| Authors | Yuxuan Chen, Arianna Bunnell, Yanqi Xu et al. |
|---|---|
| Primary category | eess.IV |
| Published | 6 May 2026 |
| Last updated at source | 6 May 2026 |
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