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Paper · arXiv

Orientation-Aware Unsupervised Domain Adaptation for Brain Tumor Classification Across Multi-Modal MRI

The clinical integration of deep learning models for brain tumor diagnosis in neuro-oncology is severely constrained by limited expert-annotated MRI data and substantial inter-institutional domain shift arising from variations in scanners, imaging protocols, and contrast settings. These challenges significantly impair model generalization in real-world settings. To address this, we propose a novel orientation-aware unsupervised domain-adaptive framework for automated brain tumor classification using mixed 2D MRI slices. Initially, a CNN with large receptive field first categorizes input slices into axial, sagittal, and coronal views. For each orientation, a CNN architecture with ResNet50 ...

AuthorsSapna Sachan, Amulya Kumar Mahto, Prashant Wagambar Patil
Primary categorycs.CV
Published5 May 2026
Last updated at source5 May 2026
cs.CV
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