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Paper · arXiv

Synthetic Data Generation for Long-Tail Medical Image Classification: A Case Study in Skin Lesions

Long-tailed class distributions are pervasive in multi-class medical datasets and pose significant challenges for deep learning models which typically underperform on tail classes with limited samples. This limitation is particularly problematic in medical applications, where rare classes often correspond to severe or high-risk diseases and therefore require high diagnostic accuracy. Existing solutions-including specialized architectures, rebalanced loss functions, and handcrafted data augmentation-offer only marginal improvements and struggle to scale due to their limited and largely deterministic variability. To address these challenges, we introduce a diffusion-model-driven synthetic d...

AuthorsJiaxiang Jiang, Mahesh Subedar, Omesh Tickoo
Primary categorycs.CV
Published4 May 2026
Last updated at source4 May 2026
cs.CV
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