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Paper · arXiv

A Universal Space of Brain Dynamics for Unveiling Cognitive Transitions and Individual Differences

Representing dynamical systems through data-driven universal spaces has proven effective; however, achieving this universality for human brain activity remains a significant challenge, further aggravated by diverse cognitive states and individual subjects. Recognizing that spatial properties reflect physical wiring while temporal properties reflect brain function, we develop Universal Brain Dynamics (UBD) to construct a universal space tailored to brain activity and quantify corresponding dynamics using a model-derived Jacobian matrix. Crucially, we validate UBD's universality by accurately predicting functional magnetic resonance imaging (fMRI) signals (Pearson's r > 0.9) across eight st...

AuthorsRonghua Zheng, Chengyuan Qian, Weiyang Ding
Primary categoryq-bio.QM
Published1 May 2026
Last updated at source1 May 2026
q-bio.QMcs.AI
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