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Paper · arXiv

Rhamba: Region-Aware Hybrid Attention-Mamba Framework for Self-Supervised Learning in Resting-State fMRI

Self-supervised pretraining is promising for large-scale neuroimaging, yet the impact of region-aware masking and hybrid sequence modeling remains underexplored. In this work, we introduce Rhamba, a region-aware pretraining framework that integrates anatomically guided masking with hybrid Attention-Mamba architectures for resting state functional magnetic resonance imaging (fMRI) analysis. Models were pretrained on the ABIDE dataset using region-aligned patch embeddings and three masking strategies (Any, Majority, and Pure) with increasing spatial specificity. We evaluated four architectural variants: a Mamba only model, an Alternate architecture with interleaved Mamba and Attention block...

AuthorsPankaj Pandey, Ruthwik Reddy Doodipala, Pratheek Eranki et al.
Primary categorycs.LG
Published2 May 2026
Last updated at source18 September 2026
cs.LGcs.AI
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