Towards patient-specific optimization for mandibular reconstruction planning based on predicted bone-union propensity
Mandibular reconstruction with vascularized bone grafts is complicated by donor-host nonunion, and virtual surgical planning produces a geometric plan rather than optimizing for bone-union propensity at the donor-host interface. We present OsteoOpt++, an image-to-decision planning loop for patient-specific mandibular reconstruction. Pre-operative computed tomography (CT) is converted into a personalized digital twin through template-to-patient registration and CT-derived updates of the muscle and temporomandibular-joint parameters. Bayesian optimization with an expected-improvement-plus acquisition rule then searches six clinically controllable cut-plane and donor-positioning variables un...
| Authors | Hamidreza Aftabi, John E. Lloyd, Amanda Ding et al. |
|---|---|
| Primary category | cs.CV |
| Published | 1 May 2026 |
| Last updated at source | 4 September 2026 |
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