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Teaching LLMs Brazilian Healthcare: Injecting Knowledge from Official Clinical Guidelines

Brazil's Unified Health System (SUS) relies on official clinical guidelines that define diagnostic criteria, treatments, dosages, and monitoring procedures for over 200 million citizens. Yet current LLMs perform poorly on this guideline-specific knowledge, and no benchmark evaluates clinical recall grounded in Brazilian Portuguese protocols. We address this gap by adapting Qwen2.5-14B-Instruct to the Brazilian clinical domain. From 178 official guidelines (~5.4M tokens), we generate ~70M tokens of synthetic data in three formats -- rephrases, wiki-style articles, and question-answer pairs -- using four generator LLMs. We then apply continual pre-training followed by Group Relative Policy ...

AuthorsHugo Abonizio, Filipe Rocha Lopes, Roberto Lotufo et al.
Primary categorycs.CL
Published1 May 2026
Last updated at source1 May 2026
cs.CL
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