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Paper · arXiv

Federated Distillation for Whole Slide Image via Gaussian-Mixture Feature Alignment and Curriculum Integration

Federated learning (FL) offers a promising framework for collaborative digital pathology by enabling model training across institutions. However, real-world deployments face heterogeneity arising from diverse multiple instance learning (MIL) architectures and heterogeneous feature extractors across institutions. We propose FedHD, a novel FL framework that performs local Gaussian-mixture feature alignment tailored for WSI analysis. Instead of exchanging model parameters, each client independently distills semantically rich synthetic feature representations aligned with the distribution of real WSIs. To preserve diagnostic diversity, FedHD adopts a one-to-one distillation strategy, generati...

AuthorsLuru Jing, Cong Cong, Yanyuan Chen et al.
Primary categorycs.CV
Published1 May 2026
Last updated at source19 May 2026
cs.CV
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