From Black-Box Confidence to Measurable Trust in Clinical AI: A Framework for Evidence, Supervision, and Staged Autonomy
Trust in clinical artificial intelligence (AI) cannot be reduced to model accuracy, fluency of generation, or overall positive user impression. In medicine, trust must be engineered as a measurable system property grounded in evidence, supervision, and operational boundaries of AI autonomy. This article proposes a practical framework for trustworthy clinical AI built around three principles: evidence, supervision, and staged autonomy. Rather than replacing deterministic clinical logic wholesale with end-to-end black-box models, the proposed approach combines a deterministic core, a patient-specific AI assistant for contextual validation, a multi-tier model escalation mechanism, and a huma...
| Authors | Serhii Zabolotnii, Viktoriia Holinko, Olha Antonenko |
|---|---|
| Primary category | cs.CL |
| Published | 29 April 2026 |
| Last updated at source | 29 April 2026 |
Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.