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Paper · arXiv

Beyond Patient Invariance: Learning Cardiac Dynamics via Action-Conditioned JEPAs

Self-supervised learning in healthcare has largely relied on invariance-based objectives, which maximize similarity between different views of the same patient. While effective for static anatomy, this paradigm is fundamentally misaligned with clinical diagnosis, as it mathematically compels the model to suppress the transient pathological changes it is intended to detect. We propose a shift towards Action-Conditioned World Models that learn to simulate the dynamics of disease progression, or Event-Conditioned. Adapting the LeJEPA framework to physiological time-series, we define pathology not as a static label, but as a transition vector acting on a patient's latent state. By predicting ...

AuthorsJose Geraldo Fernandes, Luiz Facury, Pedro Robles Dutenhefner et al.
Primary categorycs.LG
Published24 April 2026
Last updated at source24 April 2026
cs.LG
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