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Paper · arXiv

FeatEHR-LLM: Leveraging Large Language Models for Feature Engineering in Electronic Health Records

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack clinical domain awareness or assume clean, regularly sampled inputs, limiting their applicability to real-world EHR data. We present \textbf{FeatEHR-LLM}, a framework that leverages Large Language Models (LLMs) to generate clinically meaningful tabular features from irregularly sampled EHR time series. To limit patient privacy exposure, the LLM operates exclusively on dataset schemas and task descriptions rather than raw patient records. A tool-augmented ...

AuthorsHojjat Karami, David Atienza, Jean-Philippe Thiran et al.
Primary categorycs.LG
Published24 April 2026
Last updated at source24 April 2026
cs.LGcs.AI
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