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Paper · arXiv

From Pixels to Nucleotides: End-to-End Token-Based Video Compression for DNA Storage

DNA-based storage has emerged as a promising approach to the global data crisis, offering molecular-scale density and millennial-scale stability at low maintenance cost. Over the past decade, substantial progress has been made in storing text, images, and files in DNA -- yet video remains an open challenge. The difficulty is not merely technical: effective video DNA storage requires co-designing compression and molecular encoding from the ground up, a challenge that sits at the intersection of two fields that have largely evolved independently. In this work, we present HELIX, the first end-to-end neural network jointly optimizing video compression and DNA encoding -- prior approaches trea...

AuthorsCihan Ruan, Lebin Zhou, Bingqing Zhao et al.
Primary categorycs.CV
Published15 April 2026
Last updated at source15 April 2026
cs.CVcs.ET
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