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Paper · arXiv

Learning Preference-Based Objectives from Clinical Narratives for Dynamic Sepsis Treatment

Designing reward functions for reinforcement learning (RL) in healthcare remains challenging because clinically meaningful outcomes are sparse, delayed, and difficult to explicitly specify. Although structured clinical data capture physiologic states, they often fail to reflect broader aspects of patient trajectories such as treatment response, recovery dynamics, and intervention burden. Clinical narratives, by contrast, encode longitudinal clinician assessments of disease progression, treatment effectiveness, and recovery, providing a potential source of trajectory-level supervision beyond predefined outcome metrics. We propose Clinical Narrative-informed Preference Rewards (CN-PR), a fr...

AuthorsDaniel J. Tan, Jayne Hui Zhen Chan, Kai Wen Hwang et al.
Primary categorycs.AI
Published12 April 2026
Last updated at source25 May 2026
cs.AIcs.LG
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