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Paper · arXiv

CARE-ECG: Causal Agent-based Reasoning for Explainable and Counterfactual ECG Interpretation

Large language models (LLMs) enable waveform-to-text ECG interpretation and interactive clinical questioning, yet most ECG-LLM systems still rely on weak signal-text alignment and retrieval without explicit physiological or causal structure. This limits grounding, temporal reasoning, and counterfactual "what-if" analysis central to clinical decision-making. We propose CARE-ECG, a causally structured ECG-language reasoning framework that unifies representation learning, diagnosis, and explanation in a single pipeline. CARE-ECG encodes multi-lead ECGs into temporally organized latent biomarkers, performs causal graph inference for probabilistic diagnosis, and supports counterfactual assessm...

AuthorsElahe Khatibi, Ziyu Wang, Ankita Sharma et al.
Primary categorycs.LG
Published12 April 2026
Last updated at source12 April 2026
cs.LG
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