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Paper · arXiv

Active Diffusion Matching: Score-based Iterative Alignment of Cross-Modal Retinal Images

Objective: The study aims to address the challenge of aligning Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which is difficult due to their substantial differences in viewing range and the amorphous appearance of the retina. Currently, no specialized method exists for this task, and existing image alignment techniques lack accuracy. Methods: We propose Active Diffusion Matching (ADM), a novel cross-modal alignment method. ADM integrates two interdependent score-based diffusion models to jointly estimate global transformations and local deformations via an iterative Langevin Markov chain. This approach facilitates a stochastic, progressive search for optimal ali...

AuthorsKanggeon Lee, Su Jeong Song, Soochahn Lee et al.
Primary categorycs.CV
Published11 April 2026
Last updated at source11 April 2026
cs.CV
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