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Paper · arXiv

Is There Knowledge Left to Extract? Evidence of Fragility in Medically Fine-Tuned Vision-Language Models

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We evaluate four paired open-source VLMs (LLaVA vs. LLaVA-Med; Gemma vs. MedGemma) across four medical imaging tasks of increasing difficulty: brain tumor, pneumonia, skin cancer, and histopathology classification. We find that performance degrades toward near-random levels as task difficulty increases, indicating limited clinical reasoning. Medical fine-tuning provides no consistent advantage, and models are highly sensitive to prompt formulation, with minor cha...

AuthorsOliver McLaughlin, Daniel Shubin, Carsten Eickhoff et al.
Primary categorycs.CV
Published10 April 2026
Last updated at source10 April 2026
cs.CVcs.AI
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