SatIR: Scalable High-Recall Constraint-Satisfaction-Based Information Retrieval for Clinical Trials Matching
Many real-world retrieval and matching problems require more than topical relevance: a candidate must satisfy the specific constraints of one profile among many, not just be relevant to it. Clinical trials are a high-stakes instance of this challenge: they are central to evidence-based medicine, yet many struggle to meet enrollment targets, despite the availability of over half a million trials listed on ClinicalTrials.gov, which attracts approximately two million users monthly. Existing retrieval techniques, largely based on keyword and embedding-similarity matching, treat eligibility constraints as soft signals rather than binding requirements, resulting in low recall, low precision, an...
| Authors | Zikai Zhou, Yufei Jin, Yilin Xu et al. |
|---|---|
| Primary category | cs.CL |
| Published | 10 April 2026 |
| Last updated at source | 14 September 2026 |
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