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Paper · arXiv

Grounding Clinical AI Competency in Human Cognition Through the Clinical World Model and Skill-Mix Framework

The competency of any intelligent agent is bounded by its formal account of the world in which it operates. Clinical AI lacks such an account. Existing frameworks address evaluation, regulation, or system design in isolation, without a shared model of the clinical world to connect them. We introduce the Clinical World Model, a framework that formalizes care as a tripartite interaction among Patient, Provider, and Ecosystem. To formalize how any agent, whether human or artificial, transforms information into clinical action, we develop parallel decision-making architectures for providers, patients, and AI agents, grounded in validated principles of clinical cognition. The Clinical AI Skill...

AuthorsSeyed Amir Ahmad Safavi-Naini, Elahe Meftah, Josh Mohess et al.
Primary categorycs.AI
Published9 April 2026
Last updated at source9 April 2026
cs.AIcs.HCeess.SY
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