Bridging MRI and PET physiology: Untangling complementarity through orthogonal representations
Multimodal imaging analysis often relies on joint latent representations, yet these approaches rarely define what information is shared versus modality-specific. Clarifying this distinction is clinically relevant, as it delineates the irreducible contribution of each modality and informs rational acquisition strategies. We propose a subspace decomposition framework that reframes multimodal fusion as a problem of orthogonal subspace separation rather than translation. We decompose Prostate-Specific Membrane Antigen (PSMA) PET uptake into an MRI-explainable physiological envelope and an orthogonal residual reflecting signal components not expressible within the MRI feature manifold. Using m...
| Authors | Sonja Adomeit, Kartikay Tehlan, Lukas Förner et al. |
|---|---|
| Primary category | cs.CV |
| Published | 8 April 2026 |
| Last updated at source | 8 April 2026 |
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