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Paper · arXiv

Toward a universal foundation model for graph-structured data

Graphs are a central representation in biomedical research, capturing molecular interaction networks, gene regulatory circuits, cell--cell communication maps, and knowledge graphs. Despite their importance, currently there is not a broadly reusable foundation model available for graph analysis comparable to those that have transformed language and vision. Existing graph neural networks are typically trained on a single dataset and learn representations specific only to that graph's node features, topology, and label space, limiting their ability to transfer across domains. This lack of generalization is particularly problematic in biology and medicine, where networks vary substantially ac...

AuthorsSakib Mostafa, Lei Xing, Md. Tauhidul Islam
Primary categorycs.LG
Published7 April 2026
Last updated at source7 April 2026
cs.LGcs.AI
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