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Paper · arXiv

Toward Full Autonomous Laboratory Instrumentation Control with Large Language Models

The control of complex laboratory instrumentation often requires significant programming expertise, creating a barrier for researchers lacking computational skills. This work explores the potential of large language models (LLMs), such as ChatGPT, and LLM-based artificial intelligence (AI) agents to enable efficient programming and automation of scientific equipment. Through a case study involving the implementation of a setup that can be used as a single-pixel camera or a scanning photocurrent microscope, we demonstrate how ChatGPT can facilitate the creation of custom scripts for instrumentation control, significantly reducing the technical barrier for experimental customization. Buildi...

AuthorsYong Xie, Kexin He, Andres Castellanos-Gomez
Primary categorycs.AI
Published25 March 2026
Last updated at source25 March 2026
cs.AIcond-mat.mtrl-scics.HC
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