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Can Large Language Models Self-Correct in Medical Question Answering? An Exploratory Study

Large language models (LLMs) have achieved strong performance on medical question answering (medical QA), and chain-of-thought (CoT) prompting has further improved results by eliciting explicit intermediate reasoning; meanwhile, self-reflective (self-corrective) prompting has been widely claimed to enhance model reliability by prompting LLMs to critique and revise their own reasoning, yet its effectiveness in safety-critical medical settings remains unclear. In this work, we conduct an exploratory analysis of self-reflective reasoning for medical multiple-choice question answering: using GPT-4o and GPT-4o-mini, we compare standard CoT prompting with an iterative self-reflection loop and t...

AuthorsZaifu Zhan, Mengyuan Cui, Rui Zhang
Primary categorycs.CL
Published31 March 2026
Last updated at source2 April 2026
cs.CL
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