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Paper · arXiv

Multimodal Machine Learning for Early Prediction of Metastasis in a Swedish Multi-Cancer Cohort

Multimodal Machine Learning offers a holistic view of a patient's status, integrating structured and unstructured data from electronic health records (EHR). We propose a framework to predict metastasis risk one month prior to diagnosis, using six months of clinical history from EHR data. Data from four cancer cohorts collected at Karolinska University Hospital (Stockholm, Sweden) were analyzed: breast (n = 743), colon (n = 387), lung (n = 870), and prostate (n = 1890). The dataset included demographics, comorbidities, laboratory results, medications, and clinical text. We compared traditional and deep learning classifiers across single modalities and multimodal combinations, using various...

AuthorsFranco Rugolon, Korbinian Randl, Braslav Jovanovic et al.
Primary categorycs.LG
Published31 March 2026
Last updated at source31 March 2026
cs.LGq-bio.QM
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