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Paper · arXiv

Detecting low left ventricular ejection fraction from ECG using an interpretable and scalable predictor-driven framework

Low left ventricular ejection fraction (LEF) frequently remains undetected until progression to symptomatic heart failure, underscoring the need for scalable screening strategies. Although artificial intelligence-enabled electrocardiography (AI-ECG) has shown promise, existing approaches rely solely on end-to-end black-box models with limited interpretability or on tabular systems dependent on commercial ECG measurement algorithms with suboptimal performance. We introduced ECG-based Predictor-Driven LEF (ECGPD-LEF), a structured framework that integrates foundation model-derived diagnostic probabilities with interpretable modeling for detecting LEF from ECG. Trained on the benchmark EchoN...

AuthorsYa Zhou, Tianxiang Hao, Ziyi Cai et al.
Primary categorycs.LG
Published30 March 2026
Last updated at source5 April 2026
cs.LGcs.AIstat.AP
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