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Paper · arXiv

Beyond Benchmarks: A Framework for Post Deployment Validation of CT Lung Nodule Detection AI

Background: Artificial intelligence (AI) assisted lung nodule detection systems are increasingly deployed in clinical settings without site-specific validation. Performance reported under benchmark conditions may not reflect real-world behavior when acquisition parameters differ from training data. Purpose: To propose and demonstrate a physics-guided framework for evaluating the sensitivity of a deployed lung nodule detection model to systematic variation in CT acquisition parameters. Methods: Twenty-one cases from the publicly available LIDC-IDRI dataset were evaluated using a MONAI RetinaNet model pretrained on LUNA16 (fold 0, no fine-tuning). Five imaging conditions were tested: baseli...

AuthorsDaniel Soliman
Primary categoryeess.IV
Published25 March 2026
Last updated at source25 March 2026
eess.IVcs.CVphysics.med-ph
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