Automatic Segmentation of 3D CT scans with SAM2 using a zero-shot approach
Foundation models for image segmentation have shown strong generalization in natural images, yet their applicability to 3D medical imaging remains limited. In this work, we study the zero-shot use of Segment Anything Model 2 (SAM2) for automatic segmentation of volumetric CT data, without any fine-tuning or domain-specific training. We analyze how SAM2 should be applied to CT volumes and identify its main limitation: the lack of inherent volumetric awareness. To address this, we propose a set of inference-alone architectural and procedural modifications that adapt SAM2's video-based memory mechanism to 3D data by treating CT slices as ordered sequences. We conduct a systematic ablation st...
| Authors | Miquel Lopez Escoriza, Pau Amargant Alvarez |
|---|---|
| Primary category | cs.CV |
| Published | 24 March 2026 |
| Last updated at source | 24 March 2026 |
Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.