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Paper · arXiv

Sketch2CT: Multimodal Diffusion for Structure-Aware 3D Medical Volume Generation

Diffusion probabilistic models have demonstrated significant potential in generating high-quality, realistic medical images, providing a promising solution to the persistent challenge of data scarcity in the medical field. Nevertheless, producing 3D medical volumes with anatomically consistent structures under multimodal conditions remains a complex and unresolved problem. We introduce Sketch2CT, a multimodal diffusion framework for structure-aware 3D medical volume generation, jointly guided by a user-provided 2D sketch and a textual description that captures 3D geometric semantics. The framework initially generates 3D segmentation masks of the target organ from random noise, conditioned...

AuthorsDelin An, Chaoli Wang
Primary categorycs.CV
Published23 March 2026
Last updated at source23 March 2026
cs.CV
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