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Paper · arXiv

Evaluating AI-based Scientific Knowledge Synthesis with Epidemiological Systematic Reviews

Systematic literature reviews (SLRs) are a demanding and high-stakes form of scientific knowledge synthesis that remains underspecified as an evaluation setting for large language models (LLMs). We introduce AgentSLR, a large-scale evaluation harness comprising an SLR automation workflow and an expert annotated dataset covering 16,248 articles, designed to test LLM capabilities across the stages of SLRs in epidemiology. Reference annotations were derived from peer-reviewed studies on WHO priority pathogens and produced by domain experts. The harness evaluates each review stage as a separate unit with dedicated metrics enabling targeted failure analysis. We evaluated five frontier reasonin...

AuthorsShreyansh Padarha, Ryan Othniel Kearns, Tristan Naidoo et al.
Primary categorycs.IR
Published20 March 2026
Last updated at source4 June 2026
cs.IRcs.AIcs.DL
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