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Paper · arXiv

Chronological Contrastive Learning: Few-Shot Progression Assessment in Irreversible Diseases

Quantitative disease severity scoring in medical imaging is costly, time-consuming, and subject to inter-reader variability. At the same time, clinical archives contain far more longitudinal imaging data than expert-annotated severity scores. Existing self-supervised methods typically ignore this chronological structure. We introduce ChronoCon, a contrastive learning approach that replaces label-based ranking losses with rankings derived solely from the visitation order of a patient's longitudinal scans. Under the clinically plausible assumption of monotonic progression in irreversible diseases, the method learns disease-relevant representations without using any expert labels. This gener...

AuthorsClemens Watzenböck, Daniel Aletaha, Michaël Deman et al.
Primary categorycs.CV
Published23 March 2026
Last updated at source10 April 2026
cs.CVcs.AI
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