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Paper · arXiv

Towards Practical Multimodal Hospital Outbreak Detection

Rapid identification of outbreaks in hospitals is essential for controlling pathogens with epidemic potential. Although whole genome sequencing (WGS) remains the gold standard in outbreak investigations, its substantial costs and turnaround times limit its feasibility for routine surveillance, especially in less-equipped facilities. We explore three modalities as rapid alternatives: matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, antimicrobial resistance (AR) patterns, and electronic health records (EHR). We present a machine learning approach that learns discriminative features from these modalities to support outbreak detection. Multi-species ev...

AuthorsChang Liu, Jieshi Chen, Alexander J. Sundermann et al.
Primary categorycs.LG
Published20 March 2026
Last updated at source20 March 2026
cs.LG
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