Revisiting Gene Ontology Knowledge Discovery with Hierarchical Feature Selection and Virtual Study Group of AI Agents
Large language models have achieved great success in multiple challenging tasks, and their capacity can be further boosted by the emerging agentic AI techniques. This new computing paradigm has already started revolutionising the traditional scientific discovery pipelines. In this work, we propose a novel agentic AI-based knowledge discovery-oriented virtual study group that aims to extract meaningful ageing-related biological knowledge considering highly ageing-related Gene Ontology terms that are selected by hierarchical feature selection methods. We investigate the performance of the proposed agentic AI framework by considering four different model organisms' ageing-related Gene Ontolo...
| Authors | Cen Wan, Alex A. Freitas |
|---|---|
| Primary category | cs.LG |
| Published | 20 March 2026 |
| Last updated at source | 20 March 2026 |
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