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Paper · arXiv

The Validity Gap in Health AI Evaluation: A Cross-Sectional Analysis of Benchmark Composition

Background: Clinical trials rely on transparent inclusion criteria to ensure generalizability. In contrast, benchmarks validating health-related large language models (LLMs) rarely characterize the "patient" or "query" populations they contain. Without defined composition, aggregate performance metrics may misrepresent model readiness for clinical use. Methods: We analyzed 18,707 consumer health queries across six public benchmarks using LLMs as automated coding instruments to apply a standardized 16-field taxonomy profiling context, topic, and intent. Results: We identified a structural "validity gap." While benchmarks have evolved from static retrieval to interactive dialogue, clinical ...

AuthorsAlvin Rajkomar, Pavan Sudarshan, Angela Lai et al.
Primary categorycs.AI
Published18 March 2026
Last updated at source15 April 2026
cs.AI
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