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Paper · arXiv

Clinically Meaningful Explainability for NeuroAI: An ethical, technical, and clinical perspective

While explainable AI (XAI) is often heralded as a means to enhance transparency and trustworthiness in closed-loop neurotechnology for psychiatric and neurological conditions, its real-world prevalence remains low. Moreover, empirical evidence suggests that the type of explanations provided by current XAI methods often fails to align with clinicians' end-user needs. In this viewpoint, we argue that clinically meaningful explainability (CME) is essential for AI-enabled closed-loop medical neurotechnology and must be addressed from an ethical, technical, and clinical perspective. Instead of exhaustive technical detail, clinicians prioritize clinically relevant, actionable explanations, such...

AuthorsLaura Schopp, Ambra DImperio, Jalal Etesami et al.
Primary categorycs.CY
Published6 March 2026
Last updated at source6 March 2026
cs.CYcs.AIq-bio.NC
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