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Paper · arXiv

Conservative Continuous-Time Treatment Optimization

We develop a conservative continuous-time stochastic control framework for treatment optimization from irregularly sampled patient trajectories. The unknown patient dynamics are modeled as a controlled stochastic differential equation with treatment as a continuous-time control. Naive model-based optimization can exploit model errors and propose out-of-support controls, so optimizing the estimated dynamics may not optimize the true dynamics. To limit extrapolation, we add a consistent signature-based MMD regularizer on path space that penalizes treatment plans whose induced trajectory distribution deviates from observed trajectories. The resulting objective minimizes a computable upper bo...

AuthorsNora Schneider, Georg Manten, Niki Kilbertus
Primary categorycs.LG
Published17 March 2026
Last updated at source17 March 2026
cs.LGq-bio.QM
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