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Paper · arXiv

When Stability Fails: Hidden Failure Modes Of LLMS in Data-Constrained Scientific Decision-Making

Large language models (LLMs) are increasingly used as decision-support tools in data-constrained scientific workflows, where correctness and validity are critical. However, evaluation practices often emphasize stability or reproducibility across repeated runs. While these properties are desirable, stability alone does not guar- antee agreement with statistical ground truth when such references are available. We introduce a controlled behavioral evaluation framework that explicitly sep- arates four dimensions of LLM decision-making: stability, correctness, prompt sensitivity, and output validity under fixed statistical inputs. We evaluate multi- ple LLMs using a statistical gene prioritiza...

AuthorsNazia Riasat
Primary categorycs.LG
Published16 March 2026
Last updated at source16 March 2026
cs.LGcs.AIcs.CLstat.ML
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