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Paper · arXiv

TopoCL: Topological Contrastive Learning for Medical Imaging

Contrastive learning (CL) has become a powerful approach for learning representations from unlabeled images. However, existing CL methods focus predominantly on visual appearance features while neglecting topological characteristics (e.g., connectivity patterns, boundary configurations, cavity formations) that provide valuable cues for medical image analysis. To address this limitation, we propose a new topological CL framework (TopoCL) that explicitly exploits topological structures during contrastive learning for medical imaging. Specifically, we first introduce topology-aware augmentations that control topological perturbations using a relative bottleneck distance between persistence d...

AuthorsGuangyu Meng, Pengfei Gu, Peixian Liang et al.
Primary categorycs.CV
Published15 March 2026
Last updated at source15 March 2026
cs.CVcs.AI
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