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Paper · arXiv

Histo-MExNet: A Unified Framework for Real-World, Cross-Magnification, and Trustworthy Breast Cancer Histopathology

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges, we propose Histo-MExNet, a unified framework designed for scaleinvariant and uncertainty-aware classification. The model integrates DenseNet, ConvNeXt, and EfficientNet backbones within a gated multi-expert architecture, incorporates a prototype learning module for example-driven interpretability, and applies physics-informed regularization to enforce morphology preservation and spatial coherence during feature learning. Monte Carlo Dropout is used to q...

AuthorsEnam Ahmed Taufika, Md Ahasanul Arafatha, Abhijit Kumar Ghoshb et al.
Primary categorycs.CV
Published15 March 2026
Last updated at source15 March 2026
cs.CV
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