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Paper · arXiv

How Do Medical MLLMs Fail? A Study on Visual Grounding in Medical Images

Generalist multimodal large language models (MLLMs) have achieved impressive performance across a wide range of vision-language tasks. However, their performance on medical tasks, particularly in zero-shot settings where generalization is critical, remains suboptimal. A key research gap is the limited understanding of why medical MLLMs underperform in medical image interpretation. In this work, we present a pioneering systematic investigation into the visual grounding capabilities of state-of-the-art medical MLLMs. To disentangle visual grounding from semantic grounding, we design VGMED, a novel evaluation dataset developed with expert clinical guidance, explicitly assessing the visual gr...

AuthorsGuimeng Liu, Tianze Yu, Somayeh Ebrahimkhani et al.
Primary categorycs.CV
Published15 March 2026
Last updated at source15 March 2026
cs.CVcs.AI
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