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Paper · arXiv

Synthetic Melanoma Image Generation and Evaluation Using Generative Adversarial Networks

Melanoma is the most lethal form of skin cancer, and early detection is critical for improving patient outcomes. Although dermoscopy combined with deep learning has advanced automated skin-lesion analysis, progress is hindered by limited access to large, well-annotated datasets and by severe class imbalance, where melanoma images are substantially underrepresented. To address these challenges, we present the first systematic benchmarking study comparing four GAN architectures-DCGAN, StyleGAN2, and two StyleGAN3 variants (T/R)-for high-resolution melanoma-specific synthesis. We train and optimize all models on two expert-annotated benchmarks (ISIC 2018 and ISIC 2020) under unified preproce...

AuthorsPei-Yu Lin, Yidan Shen, Neville Mathew et al.
Primary categorycs.CV
Published13 March 2026
Last updated at source13 March 2026
cs.CVcs.LG
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