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Paper · arXiv

Ensuring Safety in Automated Mechanical Ventilation through Offline Reinforcement Learning and Digital Twin Verification

Mechanical ventilation (MV) is a life-saving intervention for patients with acute respiratory failure (ARF) in the ICU. However, inappropriate ventilator settings could cause ventilator-induced lung injury (VILI). Also, clinicians workload is shown to be directly linked to patient outcomes. Hence, MV should be personalized and automated to improve patient outcomes. Previous attempts to incorporate personalization and automation in MV include traditional supervised learning and offline reinforcement learning (RL) approaches, which often neglect temporal dependencies and rely excessively on mortality-based rewards. As a result, early stage physiological deterioration and the risk of VILI ar...

AuthorsHang Yu, Huidong Liu, Qingchen Zhang et al.
Primary categorycs.LG
Published11 March 2026
Last updated at source11 March 2026
cs.LG
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