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Paper · arXiv

K-MaT: Knowledge-Anchored Manifold Transport for Cross-Modal Prompt Learning in Medical Imaging

Large-scale biomedical vision-language models (VLMs) adapted on high-end imaging (e.g., CT) often fail to transfer to frontline low-end modalities (e.g., radiography), collapsing into modality-specific shortcuts. We propose K-MaT (Knowledge-Anchored Manifold Transport), a prompt-learning framework that transfers decision structures to low-end modalities without requiring low-end training images. K-MaT factorizes prompts, anchors them to clinical text descriptions, and aligns the low-end prompt manifold to the visually-grounded high-end space using Fused Gromov-Wasserstein optimal transport. We evaluate K-MaT on four cross-modal benchmarks, including dermoscopy, mammography to ultrasound, ...

AuthorsJiajun Zeng, Shadi Albarqouni
Primary categorycs.CV
Published6 March 2026
Last updated at source6 March 2026
cs.CVcs.AI
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