Clinical-Injection Transformer with Domain-Adapted MAE for Lupus Nephritis Prognosis Prediction
Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus that affects pediatric patients with significantly greater severity and worse renal outcomes compared to adults. Despite the urgent clinical need, predicting pediatric LN prognosis remains unexplored in computational pathology. Furthermore, the only existing histopathology-based approach for LN relies on multiple costly staining protocols and fails to integrate complementary clinical data. To address these gaps, we propose the first multimodal computational pathology framework for three-class treatment response prediction (complete remission, partial response, and no response) in pediatric LN, utilizing only rou...
| Authors | Yuewen Huang, Zhitao Ye, Guangnan Feng et al. |
|---|---|
| Primary category | eess.IV |
| Published | 4 March 2026 |
| Last updated at source | 4 March 2026 |
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