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Paper · arXiv

A Unified Framework for Joint Detection of Lacunes and Enlarged Perivascular Spaces

Cerebral small vessel disease (CSVD) markers, specifically enlarged perivascular spaces (EPVS) and lacunae, present a unique challenge in medical image analysis due to their radiological mimicry. Standard segmentation networks struggle with feature interference and extreme class imbalance when handling these divergent targets simultaneously. To address these issues, we propose a morphology-decoupled framework where Zero-Initialized Gated Cross-Task Attention exploits dense EPVS context to guide sparse lacune detection. Furthermore, biological and topological consistency are enforced via a mixed-supervision strategy integrating Mutual Exclusion and Centerline Dice losses. Finally, we intro...

AuthorsLucas He, Krinos Li, Hanyuan Zhang et al.
Primary categorycs.CV
Published4 March 2026
Last updated at source12 August 2026
cs.CV
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