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Paper · arXiv

WSI-INR: Implicit Neural Representations for Lesion Segmentation in Whole-Slide Images

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and treating multi-resolution views as independent samples, which leads to spatially fragmented segmentation and reduced robustness to resolution variations. To address the issues, we propose WSI-INR, a novel patch-free framework based on Implicit Neural Representations (INRs). WSI-INR models the WSI as a continuous implicit function mapping spatial coordinates directly to tissue semantics features, outputting segmentation results while preserving intrinsic sp...

AuthorsYunheng Wu, Wenqi Huang, Liangyi Wang et al.
Primary categorycs.CV
Published4 March 2026
Last updated at source4 March 2026
cs.CV
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