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Paper · arXiv

PRISM: Exploring Heterogeneous Pretrained EEG Foundation Model Transfer to Clinical Differential Diagnosis

EEG foundation models are typically pretrained on narrow-source clinical archives and evaluated on benchmarks from the same ecosystem, leaving unclear whether representations encode neural physiology or recording-distribution artifacts. We introduce PRISM (Population Representative Invariant Signal Model), a masked autoencoder ablated along two axes -- pretraining population and downstream adaptation -- with architecture and preprocessing fixed. We compare a narrow-source EU/US corpus (TUH + PhysioNet) against a geographically diverse pool augmented with multi-center South Asian clinical recordings across multiple EEG systems. Three findings emerge. First, narrow-source pretraining yields...

AuthorsJeet Bandhu Lahiri, Parshva Runwal, Arvasu Kulkarni et al.
Primary categorycs.LG
Published28 February 2026
Last updated at source28 February 2026
cs.LGcs.AI
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