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Paper · arXiv

LUMOS: Latent Universal Medical Priors for Segmentation

General vision foundation models (VFMs) have been primarily developed on natural images, and their utility for medical image segmentation is therefore often considered to depend on costly adaptation or domain-specific fine-tuning. In this paper, we revisit this assumption from a different perspective: rather than requiring VFM segmentors to relearn visual regularities, we investigate whether the low-level visual priors necessary for anatomical delineation already lie dormant within general VFMs. We observe that frozen VFMs, despite lacking medical supervision, encode transferable visual regularities. These properties are not exclusive to natural images but are also fundamental to medical ...

AuthorsZhuonan Liang, Wei Guo, Jie Gan et al.
Primary categorycs.CV
Published1 March 2026
Last updated at source10 July 2026
cs.CV
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